Mogg, Adrian J.: search on Z-Library

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1

Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases

Felder, Christian C., Goldsmith, Paul J., Jackson, Kimberley, Sanger, Helen E., Evans, David A., Mogg, Adrian J., Broad, Lisa M.

Journal:

Neuropharmacology

Year:

2018

Language:

english

File:

PDF, 1.18 MB

english, 2018

2

TRP channels as emerging targets for pain therapeutics

Broad, Lisa M, Mogg, Adrian J, Beattie, Ruth E, Ogden, Ann-Marie, Blanco, Maria-Jesus, Bleakman, David

Journal:

Expert Opinion on Therapeutic Targets

Year:

2009

Language:

english

File:

PDF, 355 KB

english, 2009

3

Epibatidine isomers and analogues: Structure–activity relationships

Richard White, John R. Malpass, Sandeep Handa, S. Richard Baker, Lisa M. Broad, Liz Folly, Adrian Mogg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 141 KB

english, 2006

4

Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes

Bradley, Sophie J, Molloy, Colin, Bundgaard, Christoffer, Mogg, Adrian J, Thompson, Karen J, Dwomoh, Louis, Sanger, Helen E, Crabtree, Michael, Brooke, Simon M, Sexton, Patrick M, Felder, Christian C,

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 5.97 MB

english, 2018

5

An antibody biosensor establishes the activation of the M1 muscarinic acetylcholine receptor during learning and memory

Butcher, Adrian J., Bradley, Sophie J., Prihandoko, Rudi, Brooke, Simon M., Mogg, Adrian, Bourgognon, Julie-Myrtille, Macedo-Hatch, Timothy, Edwards, Jennifer M., Bottrill, Andrew R., Challiss, R. A.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

6

Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH-SY5Y cells: contribution of voltage-operated Ca2+ channels and Ca2+ stores

Federico A. Dajas-Bailador, Adrian J. Mogg, Susan Wonnacott

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 241 KB

english, 2002

7

Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380

Adrian J. Mogg, Francis A. Jones, Ian A. Pullar, Christopher G.V. Sharples, Susan Wonnacott

Journal:

Neuropharmacology

Year:

2004

Language:

english

File:

PDF, 587 KB

english, 2004

8

Ligands selective for α4β2 but not α3β4 or α7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat

Janice W. Smith, Adrian Mogg, Elisiana Tafi, Eleanor Peacey, Ian A. Pullar, Philip Szekeres, Mark Tricklebank

Journal:

Psychopharmacology

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

9

The subtype-selective nicotinic acetylcholine receptor positive allosteric potentiator 2087101 differentially facilitates neurotransmission in the brain

Giovanna de Filippi, Adrian J. Mogg, Keith G. Phillips, Ruud Zwart, Emanuele Sher, Ying Chen

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 457 KB

english, 2010

10

Activation of transient receptor potential ankyrin 1 induces CGRP release from spinal cord synaptosomes

Quallo, Talisia, Gentry, Clive, Bevan, Stuart, Broad, Lisa M., Mogg, Adrian J.

Journal:

Pharmacology Research & Perspectives

Year:

2015

Language:

english

File:

PDF, 370 KB

english, 2015

11

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant M1 muscarinic acetylcholine receptor agonist.

Broad, Lisa M, Sanger, Helen E, Mogg, Adrian J, Colvin, Ellen M, Zwart, Ruud, Evans, David A, Pasqui, Francesca, Sher, Emanuele, Wishart, Graham N, Barth, Vanessa N, Felder, Christian C, Goldsmith, Pa

Journal:

British Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.23 MB

english, 2018

12

In vitro pharmacological characterization and in vivo validation of LSN3172176 a novel M1 selective muscarinic receptor agonist tracer molecule for positron emission tomography (PET)

Mogg, Adrian J, Eessalu, Thomas, Johnson, Megan, Wright, Rebecca, Sanger, Helen E, Xiou, Hongling, Crabtree, Michael, Smith, Alex, Colvin, Ellen, Schober, Douglas, Gehlert, Donald, Jesudason, Cynthia,

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

13

Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties

Leach, Katie, Loiacono, Richard E, Felder, Christian C, McKinzie, David L, Mogg, Adrian, Shaw, David B, Sexton, Patrick M, Christopoulos, Arthur

Journal:

Neuropsychopharmacology

Year:

2010

Language:

english

File:

PDF, 819 KB

english, 2010

14

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

Dage, Jeffrey L., Colvin, Ellen M., Fouillet, Antoine, Langron, Emily, Roell, William C., Li, Jingling, Mathur, Sachin X., Mogg, Adrian J., Schmitt, Matthew G., Felder, Christian C., Merchant, Kalpana

Journal:

Psychopharmacology

Year:

2014

Language:

english

File:

PDF, 2.17 MB

english, 2014

15

Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

Dennis, Siobhan H., Pasqui, Francesca, Colvin, Ellen M., Sanger, Helen, Mogg, Adrian J., Felder, Christian C., Broad, Lisa M., Fitzjohn, Steve M., Isaac, John T.R., Mellor, Jack R.

Journal:

Cerebral Cortex

Year:

2016

Language:

english

File:

PDF, 830 KB

english, 2016

16

TRPV3 in Drug Development

Broad, Lisa, Mogg, Adrian, Eberle, Elizabeth, Tolley, Marcia, Li, Dominic, Knopp, Kelly

Journal:

Pharmaceuticals

Year:

2016

Language:

english

File:

PDF, 3.94 MB

english, 2016

17

Presynaptic nicotinic receptors modulating dopamine release in the rat striatum

Susan Wonnacott, Sergio Kaiser, Adrian Mogg, Lev Soliakov, Ian W Jones

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 621 KB

english, 2000

18

Pharmacological profiling of the TRPV3 channel in recombinant and native assays

Grubisha, Olivera, Mogg, Adrian J, Sorge, Jessica L, Ball, Laura-Jayne, Sanger, Helen, Ruble, Cara L A, Folly, Elizabeth A, Ursu, Daniel, Broad, Lisa M

Journal:

British Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 2.81 MB

english, 2014

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